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Cancer treatment continues to face significant challenges, including lack of selectivity, systemic toxicity, and the adaptive resistance mechanisms of cancer cells, which limit the effectiveness of conventiona...
Nanoparticle (NP)-mediated delivery of oncolytic viral genomes (vGenomes) represents an innovative strategy to overcome the limitations of conventional oncolytic virotherapy. While traditional live virus deliv...
Compared with curcumin, bisdemethoxycurcumin, a dimethoxy derivative of curcumin, is a bioactive compound with greater anti-inflammatory and anticancer effects. However, its hydrophobic nature, rapid metabolis...
Colorectal cancer (CRC) is one of the most fatal malignant neoplasms around the world. Artemisinin (ART) displays broad anticancer properties with some drawbacks. Therefore, we tried to enhance the anticancer ...
In recent years, the rising occurrence of cancer, particularly breast cancer, has led to a growing interest in utilizing nanotechnology for treatment. As a result of the significant side effects of chemical dr...
Breast cancer remains to be one of the most prevalent cancers in women, requiring enhanced treatment approaches. This research improved the formulation of oxaliplatin-loaded PEGylated niosomes with a Central C...
Gastric cancer (GC) progression is influenced through the dysregulation of the cell death and chronic inflammation, which together foster a tumor-promoting microenvironment and enhance cancer cell survival. Ta...
Gastric cancer (GC) remains a leading cause of cancer-related mortality worldwide. The prognosis for advanced GC is poor, necessitating innovative therapeutic strategies. Small interfering RNA (siRNA) offers a...
Glioblastoma (GBM), classified as a grade IV glioma, poses a significant challenge in the medical field due to the lack of efficient early detection techniques and targeted treatment options. This review addre...
Precision medicine, through theranostics, can identify various tumors and metastatic tumors for diagnostic purposes using a radioactive drug combined with a therapeutic agent. This novel approach combines diag...
We assessed the therapeutic potential of a combination of dendrimer generation 2 (G2) + doxorubicin (DOX) + peptide IF7 on colorectal cells. The researchers utilized regular examinations to assess the dimensio...
Vincristine (VIN) inhibits microtubule formation in the mitotic spindle, effectively arresting cells in mitosis. This study aimed to develop a polyethylene glycol (PEG)-functionalized UiO-66 metal–organic fram...
One intriguing therapy option for cancer is the peptide Melittin. This study assessed the in vitro anticancer effects of Melittin, Melittin-loaded pectin, and free pectin on mammary cell lines.
Lung cancer has a poor prognosis with traditional treatments. Realgar (AS4S4), a traditional Chinese medicine, exhibits chemotherapeutic efficacy. However, its low solubility, complex dosage form, and limited the...
Glycosylation alterations have emerged as significant indicators in the landscape of cancer diagnosis, with aberrant N-glycans standing out as potential biomarkers. The existing methods for purifying N-glycans...
Since silver nanoparticles (Ag NPs) may not perform well due to low solubility and passive entry, two types of drug delivery systems based on halloysite nanotubes (HNTs) were synthesized. These systems aim to ...
Gastric cancer (GC), characterized by its high incidence and mortality, poses a great threat to public health worldwide. Although various advanced treatments have been developed for GC, the cure rate remains p...
Oral squamous cell carcinoma (OSCC) treatment represents a great challenge, since platinum-based therapeutic agents have deleterious effects on normal cells and tissues. Employing gold nanoparticles (AuNps) as...
In the realm of cancer treatment, sono–X-ray–photodynamic therapy (SXPDT) has garnered significant interest as a novel therapeutic approach. The essential part of SXPDT is the sensitizer, which under X-ray pho...
Emphasizing the significance of cancer-associated fibroblasts (CAFs), non-malignant yet pivotal players within the tumor microenvironment (TME), this review illuminates the role of inflammatory subtype (iCAF) ...
Kaposi's sarcoma-associated herpesvirus (KSHV) infection can cause a variety of tumors and is one of the leading causes of death in acquired immune deficiency syndrome (AIDS) patients. As a small molecule anti...
Colorectal cancer (CRC) represents a substantial global health burden, necessitating advancements in diagnostic and therapeutic modalities. This study aimed to investigate the potential of CeO2/GO nanoparticles (...
The original article was published in Cancer Nanotechnology 2024 15:48
To overcome the drug resistance in MCF7 cancer cells and enhance their sensitivity to cisplatin, a liposomal (Lip) nanocarrier modified by arginine-glycine-aspartic acid (RGD) to co-deliver cisplatin (Cis) and...
Cervical cancer is a significant cause of death among women worldwide, and limited treatment approaches are available for patients with metastatic or recurrent disease. Recently, the combination of nanoparticl...
Antihyperglycemic drug artemisinin (Art) has recently gained attention as a potential anticancer treatment. In this study, the poly(lactic-co-glycolic acid) (PLGA) polymer was used to create Art-containing nan...
Liver and breast cancers are among the leading causes of cancer-related deaths worldwide, prompting researchers to seek natural anticancer agents and reduce chemotherapy side effects. Red beetroot (Beta vulgaris ...
Breast cancer, a major health concern globally, often faces challenges in the non-invasive elimination of cancer cells. This has prompted researchers to explore alternative strategies, such as photothermal the...
We prepared novel plasmon-coupled silver (Ag) and silver oxide (Ag2O) nanoparticles using green synthesis and a magnetic stirrer device from lemon juice. Firstly, we prepared six Ag samples from green tea and lem...
The manipulation of CD8+ T cell functions through genetic modifications presents a novel approach to cancer immunotherapy. This study aimed to explore the effects of IL2RG-overexpressing CD8+ T cells and assess t...
Breast cancer has become the most prevalent malignancy among women, and it is estimated to comprise over 30% of all cancer cases diagnosed in women. This study evaluates the antitumor effects of a green-synthe...
Cancer, a leading cause of mortality worldwide, continues to pose significant challenges in treatment and management. Conventional therapies often face limitations, including lack of selectivity, adverse effec...
Doxorubicin (DOX) is the most common treatment for breast cancer, but its effectiveness is limited by drug resistance and dose variability. Evidence suggests that nanozymes can significantly improve drug penet...
Major therapeutic developments have been made in the prevention of head and neck cancer (HNC), and crucial measures have been implemented for the survival of patients. The advent of cancer nano-theranostic as ...
Developing a drug delivery system that can transport a higher concentration to the target cells can improve therapeutic efficacy. This study aimed to develop a novel delivery system for acetyl-11-keto-beta-bos...
Cancer cells can resist chemotherapy through various mechanisms, diminishing treatment outcomes. Research had indicated that combining miR-122 with doxorubicin (DOX) can improve hepatocellular carcinoma (HCC) ...
The Correction to this article has been published in Cancer Nanotechnology 2024 15:61
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Radiation therapy (RT) is a modality for TNBC management. Radiosensitizers can mitigate the adverse effects of RT. Applying green...
Sono-photodynamic therapy (SPDT), which combines photodynamic (PDT) and sonodynamic (SDT) therapies with sensitizers, offers new avenues for cancer treatment. Even though new sensitizers for SPDT have been syn...
To investigate the ability of extracellular vesicles (EVs) to deliver oxaliplatin to epidermal growth factor receptor (EGFR+) colorectal cancer cells and increase oxaliplatin’s cytotoxicity.
Since wound healing requires cells to repopulate a damaged area, cell migration is essential. In addition, migration plays a crucial role in cancer metastasis. Whether tumour cells can invade tissue and metast...
The purpose of this study was biogenic synthesis of silver nanoparticles using aqueous leaf extract of Cissus woodrowii (CW-AgNPs) and exploration of their role in inhibition cell proliferation of breast cancer c...
Colorectal Cancer (CRC) is the second leading cause of death among tumors worldwide. Conventional treatments are often accompanied by emerging immunotherapies, trying to reduce the burden of advanced and metas...
The original article was published in Cancer Nanotechnology 2023 14:78
Magnetic fluid hyperthermia (MFH) represents a promising therapeutic strategy in cancer utilizing the heating capabilities of magnetic nanoparticles when exposed to an alternating magnetic field (AMF). Because...
Designing and preparing a co-delivery system based on polymeric micelles have attracted in recent years. Co-delivery of anti-cancer agents within pH-sensitive polymeric micelles could provide superior advantag...
Resveratrol (RVS) is a stilbene derivative polyphenolic compound extensively recognized for its anti-inflammatory, antioxidant and anti-aging properties, along with its enormous promise in carcinoma treatment....
Anlotinib is a targeted therapy indicated for some malignancies, including advanced non-small cell lung cancer (NSCLC). However, noninvasive biomarkers for identifying patients who will benefit from this disea...
Lung cancer has been mentioned as the first and second most prevalent cancer among males and females worldwide, respectively since conventional approaches do not have enough efficiency in its suppression. Ther...
Citation Impact 2023
Journal Impact Factor: 4.5
5-year Journal Impact Factor: 5.1
Source Normalized Impact per Paper (SNIP): 0.723
SCImago Journal Rank (SJR): 0.671
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