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Fig. 6 | Cancer Nanotechnology

Fig. 6

From: Nanoparticle-mediated delivery of oncolytic viral genomes: an innovative strategy for tumor-targeted immunotherapy

Fig. 6

Schematic illustration of the mechanism of action of nanoparticle-modified virus genome. Oncolytic nanoparticles are composed of vGenomes obtained in vitro using molecular biology techniques and nanoparticles with various functions. In tumor cells, the oncolytic viral genome modified by nanoparticles reproduces all stages of the viral life cycle, thereby replicating and generating a burst of infectious virions that spread locally, infect and kill tumor cells, thereby recruiting immune cells to the TME

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Cancer Nanotechnology

ISSN: 1868-6966

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