Fig. 5

Representative macroscopic pictures of the colonic mucosa showing the frequency of tumor masses (red circles) in the control, artemisinin (ART), and artemisinin-loaded polylactic acid nanoparticles (ART-PLA NPs) groups. Multiple large-sized tumor masses are present in the colonic mucosa of dimethylhydrazine (DMH) group; few and small tumor masses are seen in the colonic mucosa of DMH + ART group; and very few and small tumor masses are detected in colonic mucosa of DMH + ART-PLA NPs group