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Table 1 Results of GC–mass analysis of the essential oil of F. vulgare

From: Anticancer properties of copolymer nanoparticles loaded with Foeniculum vulgare derivatives in Hs578T and SUM159 cancer cell lines

Compounds

Molecular formula

Retention Time

Total (%)

Recorded pharmacological activity

References

(1R)-(+)-α-Pinen

C10H16

6. 233

2.631

–

–

4-Carene

C10H16

6. 678

0.617

–

–

beta-phellandrene

C10H16

7. 490

0.369

–

–

Sabinene

C10H16

7. 544

0.884

Anti-inflammatory

Lima et al. (2016)

beta-pinene

C10H16

8. 077

1.038

Antibacterial

Lima et al. (2016)

alpha-phellandrene

C10H16

8. 460

0.512

Antibacterial

Boevé et al. (2023)

D-Limonene

C10H16

9. 403

12.291

Antibacterial, antifungal, and antitumor

Bai et al. (2016)

3-Carene

C10H16

9. 565

0.583

Antibacterial, antioxidant, and anticancer

Shu et al. (2020)

1,4-Cyclohexadiene,

1-methyl-

C7H10

10. 170

0.380

–

–

L-Fenchone

C10H16O

11. 216

12.234

Anti-inflammatory, antioxidant, antidiarrheal, antifungal, antinociceptive, and bronchodilator

Kang et al. (2019)

Bicyclo [2. 2. 1]heptane containing N,N′-diarylsquaramide

C10H16

11. 979

0.136

Anticancer, antiviral, and antibacterial

Kang et al. (2019)

2,6-Dimethyl-2,4,6-octatriene

C10H16

12. 216

1.377

–

–

Bicyclo [2. 2. 1]heptan-2-one, 1,7,7-trimethyl-

C10H16O

12. 602

1.020

–

–

3-Cyclohexen-1-ol, 4-methyl-1-(1-methylethyl)-

C10H18O

13. 506

0.136

–

–

Estragole

C10H12O

14. 197

10.778

Antimicrobial, antioxidant, anticonvulsant, and macrophage

Roy et al. (2018)

Bicyclo [2. 2. 1]heptan-2-ol, 2-ethyl-1,3,3-trimethyl-

C12H12O

14. 969

0.569

–

–

2-Cyclohexen-1-one, 2-methyl-5-(1-methylethyl)-

C10H16O

15. 459

9.156

–

–

Anethole

C10H12O

16.705

35.194

Antifungal, antibacterial, analgesic, anti-inflammatory and antioxidant

Nasır and Yabalak (2021)

Copaene

C15H24

18.461

0.218

Antibacterial and anti-inflammatory

Kang et al. (2019)

2-Propanone, 1-(4-methoxyphenyl)-

C10H12O

18.609

0.133

–

–

1H-Cyclopenta[1,3]cyclopropa[1,2]benzene

C15H24

18.740

0.186

–

–

Bicyclo [4. 4. 0]dec-1-ene, 2-isopropyl-5-methyl-9-methylene-

C15H24

19.354

0.172

–

–

Tricyclo [3. 3. 1. 13,7] decane, tricyclo [3. 3. 1. 13,7]decylidene-

C20H28

20.059

0.186

–

–

Tricyclo [3. 3. 1. 13,7] decane, tricyclo [3. 3. 1. 13,7]decylidene-

C20H28

20.636

0.240

–

–

Naphthalene, 1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)-

C15H24

21.452

0.105

–

–

Apiol

C12H14O4

23.411

0.255

Antioxidant, antifungal, anticancer, abortifacient, acaricidal, phytotoxic, antitumor, and antiproliferative agents

Kang et al. (2019)