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Table 2 Kinetic release models and the parameters obtained for UiO-66–VIN–PEG

From: PEG-functionalized UiO-66 MOFs for targeted vincristine delivery: enhanced cytotoxicity in breast and ovarian cancer cell lines

Kinetic model

Zero-order

First-order

Higuchi

Korsmeyer–Peppas

Ct = C0 + K0t

LogC = LogC0 + Kt/2.303

Q = KH \(\surd t\)

Mt/Mꝏ = Kt.tn

r2

r2

r2

r2

n*

VIN (aq)

pH 7.4

0.5397

0.9150

0.7144

0.8106

0.5249

UiO-66–VIN

pH 7.4

0.7928

0.8571

0.9244

0.9374

0.5515

pH 5.4

0.7758

0.8880

0.9115

0.9211

0.5344

UiO-66–VIN–PEG

pH 7.4

0.8512

0.8965

0.9595

0.9537

0.6460

pH 5.4

0.7833

0.8490

0.9177

0.9380

0.5857

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Cancer Nanotechnology

ISSN: 1868-6966

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