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Table 1 Comparative efficacy of various clinical imaging modalities with potential of multimodal applications and their pros and cons

From: Updates and current states on liposomal vehicles for tumor targeting: precision therapy in the spotlight

Imaging modality

Pros

Cons

CT1

X-ray

Fast imaging

High depth penetration

High spatial resolution

Low sensitivity

Poor soft tissue contrast

Risk of radiation

MRI2

Without risk of radiation

High spatial resolution

High soft tissue contrast

Without penetration limit to tumors

Expensive

Long imaging time

Poor sensibility

PET3

SPECT4

Unlimited depth of penetration

High sensitivity

Fast imaging

Low spatial resolution

Risk of radiation

Expensive

US5

High sensitivity

High spatial resolution

Real-time

Low cost

Without risk of radiation

Rapid

Safe

Operator dependent

Limited penetration

Low resolution

Optical imaging

High sensitivity

Real-time

Cost-effective

Low penetration depth

Low spatial resolution

  1. 1Computed tomography
  2. 2Magnetic resonance imaging
  3. 3Positron emission tomography
  4. 4Single-photon emission tomography
  5. 5Ultrasound