Fig. 7

Comparison of colon tissue indices of the different groups. Normal tissue presents in the control group. Aberrant crypt foci (ACF) with dysplasia are shown with the down arrow. The epithelium displays nuclear stratification with rounded nuclei. There is a marked depletion of goblet cells in the dysplastic crypts. Mitosis (right arrow) was observed in DMH and therapeutic groups. Magnification 40 × , H&E stain