Fig. 5

Representative anatomy and angiography images of NUDE Balb/c mice bearing human lung cancer (A549). Mice were treated with (B, D, F) or without (A, C, E) MFH. In MFH-treated mice, the animals were intratumorally injected (0.2 mL) with Mg_0.1-γ-Fe₂O₃(mPEG-silane)_0.5 nanoparticles (3 mg·mL⁻¹) and subjected to an AMF for 30 min (B 23 mT, H₀ 18.3 kA·m⁻¹, f 110.1 kHz). Non-treated mice were served as controls (please see the experiment section). T2-weighted anatomy scans (A–D) was performed using the Turbo RARE sequence (TR 4500 ms, TE 30 ms, FA 180.0 deg, TA 19 min12 s, FOV 32 × 32 mm, MTX 256 × 256) in the axial (A, B) and coronal (C, D) plane. Angiography imaging (E, F) angio-MRI TOF (time-of-flight) was performed using the FLASH sequence with the following parameters: TR 17 ms, TE 4.5 ms, FA 70 deg, TA 11min6s, FOV 32 × 32 mm, MTX 256 × 256