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Table 2 Combination Index (CI) of different ratios of free DOX/DTX in both 4T1 and TUBO cell lines

From: pH-sensitive polymeric micelles enhance the co-delivery of doxorubicin and docetaxel: an emerging modality for treating breast cancer

DOX/DTX

DOX/DTX molar ratio

IC50, DOX (ÎœM)

CI 4T1

IC50, DOX (ÎœM)

CI TUBO

 

(1:5)

1.10

0.706

1.26

0.522

(5:1)

1.98

1.08

1.05

0.518

(1:10)

2.84

2.21

3.16

1.246

(10:1)

2.156

1.978

2.16

0.941

(1:1)

1.21

0.67

1.03

0.4

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Cancer Nanotechnology

ISSN: 1868-6966

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