Fig. 6

Effects of melittin, alginate lyase and SiO2–alginate–melittin conjugation on the cell migration and invasion in the ovarian cells SKOV3. A, migration of ovarian cancer cells among different groups after 0-, 6-, 24- and 36 h culture. B, relative distance of wound sites among different groups. C, cell invasion among different groups. D, invading cell numbers among different groups. n = 3 for each group. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 vs the CG group