Fig. 3
From: Application of tumor microparticles in tumor prevention and treatment
Schematic showing mechanism of T-MPs as oral tumor vaccine (Dong et al. 2017). Orally administered T-MPs could not only activate the NOD2 signaling for CCL2 production in intestinal epithelial cell and DC recruitment, but also be transported to the basolateral site by intestinal epithelial cell and captured by DC, inducing T cell anti-tumor immunity