Adapted from ref. (Tan et al. 2020) with permission from Wiley–VCH GmbH copyright 2020; adapted from ref. (Mu et al. 2021) with permission from Elsevier B.V. copyright 2021
Chemotherapy combined with chemodynamic therapy. a Illustrations of iRPPA@TMZ/MnO for MRI-guided synergistic chemotherapy/CDT for glioma (Tan et al. 2020). b The nanoreactor penetrates the BBB and targets glioblastoma therapy using CDT and chemotherapy (Mu et al. 2021).