Fig. 4

Preparation and Characterization of TGFβ-1 siRNA LNP. A Particle size of TGFβ-1 siRNA LNP. B Average zeta-potential of TGFβ-1 siRNA LNP in pH 6.0 and pH 7.4 buffers. C TEM images of TGFβ-1 siRNA LNP. D Sample of NC siRNA LNP and TGFβ-1 siRNA LNP. E IC50 of cabazitaxel API and CTX-HSA-NPs on A549/T cells. F Combined inhibitory effect of CTX-HSA-NPs combined with TGFβ-1 siRNA LNP on A549/T cells. G Cytotoxicity of cabazitaxel API and CTX-HSA-NPs on A549/T cells. H The paclitaxel RI of A549/T cells