Fig. 10

TGFβ-1 siRNA LNP combined with CTX-HSA-NPs downregulated TGFβ-1 protein expression in tumor tissues. A TGFβ-1 expression level in nude mice bearing paclitaxel-resistant non-small cell lung cancer after treatment. B The average optical density values of tumor immunohistochemical sections from nude mice bearing paclitaxel-resistant non-small cell lung cancer after treatment. (*P < 0.05, **P < 0.01) (scale bar = 50 μm) (n = 4)