Fig. 4

HCT116 cancer cell proliferation. The effect of RX-based free and nano-therapeutic regimens (RX, RX-CS NPs (F1), RX-CS NPs (F2), and RX-HA-CS nanoparticles on colorectal cancerous cell line (HCT116)). The cells were treated with these free and nano-regimens using different doses ranging from 0 µM “control” to 100 µM over 24 h (A) and 48 h (B). RX: raloxifene; HA: hyaluronic acid; CS: chitosan; NPs: nanoparticles