Fig. 9
From: Nanoparticles for MRI-guided radiation therapy: a review
(Reprinted with permission from Tanimoto and Kuribayashi (2006), copyright Elsevier, 2006 [arrows enhanced from original])
Dynamic MRI (left) vs SPION-enhanced MRI (right) in a patient with hepatocellular carcinoma (SPION type not specified). On the dynamic MR image, a number of enhancing lesions (arrows) are seen. On the SPION-enhanced MRI, all but one of these are suppressed, with only the hepatocellular carcinoma with reduced SPION uptake being apparent. At surgery, only the lesion present on the SPION-enhanced sequence was found to be malignant