Fig. 4

Apoptosis and proliferation process. A AO-EB fluorescent staining assay; scale bar is 200 µm. B Cell proliferation study by EdU test; scale bar is 200 µm. C-F Western blot analysis of Bcl-2, BAX, and Cl-Caspase 3 expression, * represents p < 0.05 and ** represents p < 0.01. PBS (a), MONs@MOF-199 (b), free DOX/SOR (c), D/S@MM (d), and D/S@SPMM (e)