Fig. 5

Fluorescence microscopy images of CurtoCK-AuNP-treated AGS cells stained with A Hoechst and propidium iodide dyes. The green arrows in the pictures indicate fragmented nuclei with condensed chromatin, meaning a damaged nucleus. The staining results of were quantified using Image J software. B Fluorescence microscopy images of mitochondrial morphology of CurtoCK-AuNP-treated AGS cells stained with MitoTracker dye. Medium alone and cisplatin (50 μM) were used as negative (NC) and positive (PC) controls, respectively. The asterisks on each column indicate significant difference between NC and each sample. *p < 0.05, **p < 0.01, ***p < 0.001