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Fig. 2 | Cancer Nanotechnology

Fig. 2

From: Inhibition of ABCC9 by zinc oxide nanoparticles induces ferroptosis and inhibits progression, attenuates doxorubicin resistance in breast cancer

Fig. 2

The overexpression of ABCC9 reverses erastin-induced ferroptosis of BC cells. A–K The MDA-MB-231 and MDA-MB-468 cells were treated with erastin (5 µM) and ABCC9 overexpressing vector. A The presence of ABCC9 was analyzed by qPCR. B, C The cell viability was determined by CCK-8 assays. D, E The cell proliferation was detected by Edu analysis. The levels of GSH (F), MDA (G), lipid ROS (H), and iron (I) were detected. J, K The expression of GPX4 and SLC7A11 was measured by Western blot analysis. **P < 0.01

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Cancer Nanotechnology

ISSN: 1868-6966

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