Fig. 5

NPDOX/siPD-L1 regulated the populations of matured dendritic cells and cytotoxic T cells and cytokine expression patterns in the tumor tissues. a–d Flow cytometry was used to analyze CD45+CD11b+CD11c+ DCs and CD8+ cytotoxic T cells. e–g The expressions of TGF-β, IL12p70, and IFN-γ in tumor tissues were determined using ELISA. Data were represented as mean ± SD (n = 8). *p < 0.05, **p < 0.01, ***p < 0.001